1. Blood is the fluid connective tissue.
2. The total volume of blood in adult human being is about 5-6 ltrs.
3. Study of blood is the Haematology.
Granulocytes in the blood of man:
1. Granulocytes possess two types of granules., they are Specific granules and the Azurophilic granules.
2. They have lobed nucleus, that may assume different shapes. Hence they are polymrphonuclear leucocytes.
3. They are non dividing cells.
4. Their life span is a few days.
Granulocytes are of three types. They are :
• Nuetrophils constitute about 62% of leucocytes.
• Necleus consists of 2 to 5 lobes. Hence they exhibit great degree of necluer poly morphism – poly morphonucluer leucocytes.
• Cytoplasm shows small specific granules, that are stained by neutral dyes.
• They are active phagocytes.
• Dead neutrophils + bacteria+ tissue fluid = pus.
• They constitute about 2.3% of leucocytes.
• They have bilobed neclues.
• Cytoplasm has many large specific granules, that are strained by eosin.
• An increase in number of esinophils in blood is eosinophilia.
• They also engulf antigen- antibody complexes.
• They constitute about 0.4% of leucocytes.
• Necleus is divided into irregular lobes.
• Cytplasm has fewer, irregular specific granules, that are stained by basic dyes.
• They contin heparin and histamine.
• They supplement the functions of mast cells by migrating into connective tissue.
Agranulocytes in the blood of man:
1. Agranulocytes do not have specific granules by they contain azurophilic granules.
2. The nucleus is unlobed.
3. Agranulocytes include Lymphocytes and Monocytes.
1. They constitute about 30% leucocytes.
2. They are spherical cells.
3. The nucleus is unlobed, spherical.
4. They play important role in immune reactions.
5. These are the only type of leucocytes that return from the blood, after diapedesis.
1. They constitute about 5.3% of leucocytes.
2. Their nucleus is kidney shaped.
3. After entering connective tissue, monocytes differentiate into macrophages.
1. Human body contains 60% of fluid by weight .
2. Of this about 2/3rd is intracellular fluid ( inside the cell) and 1/3rd is extracellular fluid –ECF( out side the cell)
3. The extracellular fluid includes –intercellular fluid, blood palsma.
4. The interstitial fluid which passes into the lymphocytic vessels is called lymph.